Katina Dorton - 17 Oct 2025 Form 4 Insider Report for Prelude Therapeutics Inc (PRLD)

Role: Director
Signature: /s/ Bryant D. Lim, Attorney-in-Fact
Issuer symbol: PRLD
Transactions as of: 17 Oct 2025
Net transactions value: $0
Form type: 4
Filing time: 20 Oct 2025, 16:16:21 UTC
Previous filing: 18 Aug 2025
Next filing: 05 Jan 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Dorton Katina	Director	C/O PRELUDE THERAPEUTICS INCORPORATED, 175 INNOVATION BOULEVARD, WILMINGTON	/s/ Bryant D. Lim, Attorney-in-Fact	20 Oct 2025	0001617541

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	PRLD	Director Stock Option (Right to Buy)	Award	$0	+76,000		$0.000000	76,000	17 Oct 2025	Common Stock	76,000	$1.19	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The option award vests over a three year period equally one-thirty-sixth per month, subject to Reporting Person's continued service to the Company on each vesting date.