| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| GOLDSMITH MARK A | President and Chief Executive Officer, Director | C/O REVOLUTION MEDICINES, INC., 700 SAGINAW DRIVE, REDWOOD CITY | /s/ Jack Anders, as attorney-in fact for Mark A. Goldsmith | 03 Mar 2026 | 0001246842 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | RVMD | Common Stock | Award | $0 | +57,100 | +25% | $0.000000 | 289,569 | 01 Mar 2026 | Direct | F1, F2 |
| transaction | RVMD | Common Stock | Options Exercise | $122,700 | +30,000 | +10% | $4.09 | 319,569 | 02 Mar 2026 | Direct | F1, F3 |
| transaction | RVMD | Common Stock | Sale | $68,720 | -700 | -0.22% | $98.17 | 318,869 | 02 Mar 2026 | Direct | F1, F3, F4 |
| transaction | RVMD | Common Stock | Sale | $349,150 | -3,500 | -1.1% | $99.76 | 315,369 | 02 Mar 2026 | Direct | F1, F3, F5 |
| transaction | RVMD | Common Stock | Sale | $364,659 | -3,620 | -1.1% | $100.73 | 311,749 | 02 Mar 2026 | Direct | F1, F3, F6 |
| transaction | RVMD | Common Stock | Sale | $2,167,075 | -21,329 | -6.8% | $101.60 | 290,420 | 02 Mar 2026 | Direct | F1, F3, F7 |
| transaction | RVMD | Common Stock | Sale | $86,972 | -851 | -0.29% | $102.20 | 289,569 | 02 Mar 2026 | Direct | F1, F3, F8 |
| transaction | RVMD | Common Stock | Sale | $9,831 | -100 | -0.15% | $98.31 | 67,324 | 02 Mar 2026 | Trust | F10 |
| transaction | RVMD | Common Stock | Sale | $40,049 | -400 | -0.59% | $100.12 | 66,924 | 02 Mar 2026 | Trust | F10, F11 |
| transaction | RVMD | Common Stock | Sale | $172,506 | -1,700 | -2.5% | $101.47 | 65,224 | 02 Mar 2026 | Trust | F10, F12 |
| transaction | RVMD | Common Stock | Sale | $81,599 | -800 | -1.2% | $102.00 | 64,424 | 02 Mar 2026 | Trust | F10, F13 |
| transaction | RVMD | Common Stock | Sale | $9,829 | -100 | -0.15% | $98.29 | 67,324 | 02 Mar 2026 | Trust | F14 |
| transaction | RVMD | Common Stock | Sale | $60,116 | -600 | -0.89% | $100.19 | 66,724 | 02 Mar 2026 | Trust | F14, F15 |
| transaction | RVMD | Common Stock | Sale | $213,432 | -2,100 | -3.1% | $101.63 | 64,624 | 02 Mar 2026 | Trust | F14, F16 |
| transaction | RVMD | Common Stock | Sale | $20,416 | -200 | -0.31% | $102.08 | 64,424 | 02 Mar 2026 | Trust | F14 |
| holding | RVMD | Common Stock | 594,060 | 01 Mar 2026 | Trust | F2, F9 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | RVMD | Stock Option (Right to Buy) | Award | $0 | +128,600 | $0.000000 | 128,600 | 01 Mar 2026 | Common Stock | 128,600 | $102.02 | Direct | F17 | |
| transaction | RVMD | Stock Option (Right to Buy) | Options Exercise | $0 | -30,000 | -39% | $0.000000 | 47,708 | 02 Mar 2026 | Common Stock | 30,000 | $4.09 | Direct | F1 |
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
| Id | Content |
|---|---|
| F1 | Includes 225,863 restricted stock units. |
| F2 | Reflects the transfer of 24,010 shares to the Mark A. Goldsmith and Anne E. Midler 2002 Revocable Living Trust. |
| F3 | Transaction made pursuant to a 10b5-1 trading plan adopted by Mark A. Goldsmith on December 19, 2024. |
| F4 | This transaction was executed in multiple trades at prices ranging from $97.83 to $98.38. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F5 | This transaction was executed in multiple trades at prices ranging from $99.12 to $100.07. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F6 | This transaction was executed in multiple trades at prices ranging from $100.14 to $101.13. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F7 | This transaction was executed in multiple trades at prices ranging from $101.14 to $102.11. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F8 | This transaction was executed in multiple trades at prices ranging from $102.14 to $102.32. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F9 | Held by Mark A. Goldsmith and Anne E. Midler 2002 Revocable Living Trust. |
| F10 | Held by Jonathan Goldsmith Revocable Trust. |
| F11 | This transaction was executed in multiple trades at prices ranging from $99.79 to $100.71. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F12 | This transaction was executed in multiple trades at prices ranging from $100.81 to $101.79. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F13 | This transaction was executed in multiple trades at prices ranging from $101.82 to $102.14. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F14 | Held by Rebecca Goldsmith Revocable Trust. |
| F15 | This transaction was executed in multiple trades at prices ranging from $99.80 to $100.71. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F16 | This transaction was executed in multiple trades at prices ranging from $101.07 to $102.02. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F17 | One forty-eighth (1/48th) of the shares initially subject to the option will vest on each monthly anniversary measured from March 1, 2026 (the "Vesting Commencement Date"), so that 100% of the shares subject to the option will be fully vested and exercisable as of the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date. |
President and Chief Executive Officer