Laura A. Williams - 20 Feb 2026 Form 4 Insider Report for ARDELYX, INC. (ARDX)

Role: Chief Patient Officer and interim Chief Medical Officer
Signature: /s/ Elizabeth Grammer, Attorney-in-Fact for Laura A. Williams
Issuer symbol: ARDX
Transactions as of: 20 Feb 2026
Net transactions value: -$47,803
Form type: 4
Filing time: 23 Feb 2026, 20:47:47 UTC
Previous filing: 26 Jan 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Williams Laura A	Chief Patient Officer and interim Chief Medical Officer	C/O ARDELYX, INC., 400 FIFTH AVENUE, SUITE 210, WALTHAM	/s/ Elizabeth Grammer, Attorney-in-Fact for Laura A. Williams	23 Feb 2026	0001869194

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ARDX	Common Stock	Sale	$42,181	-7,192	-1.6%	$5.86	437,066	20 Feb 2026	Direct	F1
transaction	ARDX	Common Stock	Sale	$5,622	-984	-0.23%	$5.71	436,082	20 Feb 2026	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.

Remarks:

Chief Patient Officer and interim Chief Medical Officer