| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Ward Shane | COO & CLO | 6310 NANCY RIDGE DRIVE, SUITE 101, SAN DIEGO | /s/ Shane Ward | 12 Dec 2025 | 0001638380 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CDTX | Common Stock | Tax liability | $3,303,004 | -15,041 | -38% | $219.60 | 24,633 | 10 Dec 2025 | Direct | F1 |
| transaction | CDTX | Common Stock | Options Exercise | $58,289 | +3,500 | +14% | $16.65 | 28,133 | 10 Dec 2025 | Direct | |
| transaction | CDTX | Common Stock | Options Exercise | $130,472 | +6,459 | +23% | $20.20 | 34,592 | 10 Dec 2025 | Direct | |
| transaction | CDTX | Common Stock | Sale | $2,191,747 | -9,959 | -28% | $220.08 | 25,033 | 10 Dec 2025 | Direct | F2 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CDTX | Employee Stock Option (right to buy) | Options Exercise | $0 | -3,500 | -100% | $0.000000 | 0 | 10 Dec 2025 | Common Stock | 3,500 | $16.65 | Direct | F3, F4 |
| transaction | CDTX | Employee Stock Option (right to buy) | Options Exercise | $0 | -6,459 | -51% | $0.000000 | 6,207 | 10 Dec 2025 | Common Stock | 6,459 | $20.20 | Direct | F4, F5 |
| Id | Content |
|---|---|
| F1 | Shares withheld for taxes on RSU vesting. |
| F2 | Includes 400 shares acquired pursuant to the Issuer's Employee Stock Purchase Plan (ESPP), representing 200 shares purchased on each of the following dates: May 20, 2025; and November 20, 2025. |
| F3 | The option shall vest and become exercisable in a series of thirty-six (36) successive equal monthly installments measured from the Vesting Commencement Date of March 31, 2022. |
| F4 | The number of securities reported herein have been adjusted to reflect the 1-for-20 reverse stock split effected by the Issuer on April 24, 2024. |
| F5 | The option shall vest and become exercisable in a series of thirty-six (36) successive equal monthly installments measured from the Vesting Commencement Date of March 27, 2023. |