Andrew Craig Miller - 01 Dec 2022 Form 4 Insider Report for Karuna Therapeutics, Inc.

Role: Chief Operating Officer
Signature: /s/ Troy Ignelzi, Attorney-in-Fact
Issuer symbol: N/A
Transactions as of: 01 Dec 2022
Net transactions value: -$3,421,222
Form type: 4
Filing time: 02 Dec 2022, 16:00:57 UTC
Previous filing: 14 Nov 2022
Next filing: 22 Dec 2022
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	KRTX	Common Stock	Options Exercise	$1,818	+250	+0.98%	$7.27^*	25,750	02 Dec 2022	Direct
transaction	KRTX	Common Stock	Options Exercise	$1,460	+500	+1.9%	$2.92^*	26,250	02 Dec 2022	Direct
transaction	KRTX	Common Stock	Sale	$3,424,500	-15,000	-57%	$228.30	11,250	01 Dec 2022	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	KRTX	Option (right to buy)	Options Exercise	$0	-250	-2.1%	$0.000000	11,578	02 Dec 2022	Common Stock	250	$7.27	Direct	F2
transaction	KRTX	Option (right to buy)	Options Exercise	$0	-500	-0.9%	$0.000000	54,917	02 Dec 2022	Common Stock	500	$2.92	Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 16, 2022.
F2	This option vested as to 1/30th of the shares underlying the option award on each one month anniversary of the vesting commencement date of August 15, 2018.
F3	This option vested as to 1/16th of the shares underlying the option award on the vesting commencement date of July 18, 2016 and as to an additional 1/16th of the shares on each three month anniversary thereafter.