Stephen K. Brannan - 01 Dec 2021 Form 4 Insider Report for Karuna Therapeutics, Inc.

Role: Chief Medical Officer
Signature: /s/ Troy Ignelzi, Attorney-in-Fact
Issuer symbol: N/A
Transactions as of: 01 Dec 2021
Net transactions value: -$916,053
Form type: 4
Filing time: 02 Dec 2021, 16:20:13 UTC
Previous filing: 03 Nov 2021
Next filing: 03 Jan 2022
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	KRTX	Common Stock	Options Exercise	$13,625	+2,500	+14%	$5.45^*	20,000	01 Dec 2021	Direct
transaction	KRTX	Common Stock	Options Exercise	$56,183	+7,728	+39%	$7.27^*	27,728	01 Dec 2021	Direct
transaction	KRTX	Common Stock	Sale	$985,861	-7,728	-28%	$127.57	20,000	01 Dec 2021	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	KRTX	Option (right to buy)	Options Exercise	$0	-2,500	-5.1%	$0.000000	46,204	01 Dec 2021	Common Stock	2,500	$5.45	Direct	F2
transaction	KRTX	Option (right to buy)	Options Exercise	$0	-7,728	-16%	$0.000000	40,302	01 Dec 2021	Common Stock	7,728	$7.27	Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 1, 2021.
F2	This option vested as to 25% of the shares on the first anniversary of the vesting commencement date of March 1, 2017, with additional vesting as to 12.5% of the shares underlying the option award at the end of each six month period thereafter.
F3	This option vests as to 12.5% of the shares underlying the option award on each six month anniversary following the vesting commencement date of August 8, 2018.