Bassil I. Dahiyat - 19 Dec 2025 Form 4 Insider Report for Xencor Inc (XNCR)

Role: PRESIDENT & CEO, Director
Signature: /s/ Celia E. Eckert, Attorney-in-Fact
Issuer symbol: XNCR
Transactions as of: 19 Dec 2025
Net transactions value: -$233,100
Form type: 4
Filing time: 23 Dec 2025, 16:01:38 UTC
Previous filing: 02 Jul 2025
Next filing: 04 Mar 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Dahiyat Bassil I	PRESIDENT & CEO, Director	C/O XENCOR, INC., 465 N HALSTEAD STREET, SUITE 200, PASADENA	/s/ Celia E. Eckert, Attorney-in-Fact	23 Dec 2025	0001591312

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	XNCR	Common Stock	Options Exercise	$1,430,856	+114,377	+25%	$12.51	581,012	19 Dec 2025	Direct	F1
transaction	XNCR	Common Stock	Sale	$1,796,863	-114,377	-20%	$15.71	466,635	19 Dec 2025	Direct	F2
transaction	XNCR	Common Stock	Options Exercise	$132,906	+10,624	+2.3%	$12.51	477,259	22 Dec 2025	Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	XNCR	Stock Option (Right to Buy)	Options Exercise	$0	-114,377	-92%	$0.000000	10,624	19 Dec 2025	Common Stock	114,377	$12.51	Direct	F3, F4, F5
transaction	XNCR	Stock Option (Right to Buy)	Options Exercise	$0	-10,624	-100%	$0.000000	0	22 Dec 2025	Common Stock	10,624	$12.51	Direct	F3, F4

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Includes the following shares acquired by the Reporting Person pursuant to the Issuer's Employee Stock Purchase Plan: 707 shares acquired on June 10, 2025 and 509 shares on December 10, 2025.
F2	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $15.52 to $15.92, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.
F3	Represents the exercise of an expiring option grant.
F4	25% of the shares subject to the option vested on the one year anniversary of January 26, 2016 (the "Vesting Commencement Date"), and 1/48th of the shares vested monthly thereafter, such that the option was fully vested and exercisable on the four year anniversary of the Vesting Commencement Date.
F5	The Reporting Person previously transferred 124,999 shares underlying the stock option to his ex-spouse. The Reporting Person no longer reports as beneficially owned any securities owned by his ex-spouse.