John Patrick Shannon Jr. - 05 Jan 2026 Form 4 Insider Report for Xeris Biopharma Holdings, Inc. (XERS)

Signature
/s/ Beth Hecht, Attorney-in-Fact
Issuer symbol
XERS
Transactions as of
05 Jan 2026
Net transactions value
-$26,259
Form type
4
Filing time
06 Jan 2026, 18:14:28 UTC
Previous filing
17 Nov 2025
Next filing
02 Feb 2026

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Shannon John Patrick Jr Chief Executive Officer and Director, Director C/O XERIS BIOPHARMA HOLDINGS, INC., 1375 WEST FULTON STREET, SUITE 1300, CHICAGO /s/ Beth Hecht, Attorney-in-Fact 06 Jan 2026 0001553595

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction XERS Common Stock Sale $176,257 -24,907 -0.91% $7.08 2,705,346 05 Jan 2026 Direct F1, F2
transaction XERS Common Stock Options Exercise $99,611 +64,265 +2.4% $1.55 2,769,611 05 Jan 2026 Direct
transaction XERS Common Stock Options Exercise $38,961 +25,136 +0.91% $1.55 2,794,747 05 Jan 2026 Direct
transaction XERS Common Stock Options Exercise $11,426 +2,900 +0.1% $3.94 2,797,647 05 Jan 2026 Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction XERS Stock Option (Right to Buy) Options Exercise $0 -64,265 -100% $0.000000 0 05 Jan 2026 Common Stock 64,265 $1.55 Direct F3
transaction XERS Stock Option (Right to Buy) Options Exercise $0 -25,136 -100% $0.000000 0 05 Jan 2026 Common Stock 25,136 $1.55 Direct F4
transaction XERS Stock Option (Right to Buy) Options Exercise $0 -2,900 -2.9% $0.000000 97,100 05 Jan 2026 Common Stock 2,900 $3.94 Direct F5
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.
F2 The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $7.040 to $7.350, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.
F3 The reporting person received the stock options on February 4, 2017 pursuant to an award under the Company's 2011 Stock Option/Stock Issuance Plan. 25% of the options vested on the first anniversary of the vesting commencement date, and the remaining 75% of options vested in equal monthly installments over the following three (3) years subject to continued employment through such vesting date.
F4 The reporting person received the stock options on June 12, 2017 pursuant to an award under the Company's 2011 Stock Option/Stock Issuance Plan. 25% of the options vested on the first anniversary of the vesting commencement date, and the remaining 75% of options vested in equal monthly installments over the following three (3) years subject to continued employment through such vesting date.
F5 The reporting person received the stock options on August 26, 2020 pursuant to an award under the Company's 2018 Stock Option/Stock Issuance Plan. 25% of the options vested on the first anniversary of the vesting commencement date, and the remaining 75% of options vested in equal monthly installments over the following three (3) years subject to continued employment through such vesting date.

Remarks:

Chief Executive Officer and Director