| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Sibold William John | President and CEO, Director | C/O MADRIGAL PHARMACEUTICALS, INC., 200 BARR HARBOR DRIVE, SUITE 200, WEST CONSHOHOCKEN | /s/ Mardi Dier, as Attorney-in-Fact | 09 Sep 2025 | 0001518611 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | MDGL | Common Stock | Sale | $3,243,741 | -7,279 | -6.6% | $445.63 | 102,474 | 09 Sep 2025 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | The sale reported on this Form 4 represents the number of shares sold by the Issuer on behalf of the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. |