Cedric Francois - 22 Jan 2026 Form 4 Insider Report for Apellis Pharmaceuticals, Inc. (APLS)

Role: Chief Executive Officer, Director
Signature: /s/ David Watson, attorney-in-fact for Cedric Francois
Issuer symbol: APLS
Transactions as of: 22 Jan 2026
Net transactions value: -$591,845
Form type: 4
Filing time: 23 Jan 2026, 16:09:41 UTC
Previous filing: 21 Jan 2026
Next filing: 30 Jan 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Francois Cedric	Chief Executive Officer, Director	C/O APELLIS PHARMACEUTICALS, INC., 100 FIFTH AVENUE, 3RD FLOOR, WALTHAM	/s/ David Watson, attorney-in-fact for Cedric Francois	23 Jan 2026	0001658080

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	APLS	Common Stock	Sale	$591,845	-27,192	-8.7%	$21.77	286,045	22 Jan 2026	Direct	F1
holding	APLS	Common Stock						307,946	22 Jan 2026	Indirect Owner (The Cedric Francois Irrevocable Trust of 2023 - 2)	F2
holding	APLS	Common Stock						472,065	22 Jan 2026	Indirect Owner (The Cedric Francois Irrevocable Trust of 2023)	F3
holding	APLS	Common Stock						300,000	22 Jan 2026	Indirect Owner (The Francois Grossi Trust)	F4
holding	APLS	Common Stock						234,411	22 Jan 2026	Indirect Owner (The Francois-DuBois Educational Trust)	F5

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	This represents shares sold to cover tax withholding on the Restricted Stock Units released on January 21, 2026.
F2	The securities are held by The Cedric Francois Irrevocable Trust of 2023 - 2. William V. A. Zorn is the trustee of The Cedric Francois Irrevocable Trust of 2023 - 2. The reporting person disclaims beneficial ownership over the shares held by The Cedric Francois Irrevocable Trust of 2023 - 2 except to the extent of his pecuniary interest therein.
F3	The securities are held by The Cedric Francois Irrevocable Trust of 2023. William V. A. Zorn is the trustee of The Cedric Francois Irrevocable Trust of 2023. The reporting person disclaims beneficial ownership over the shares held by The Cedric Francois Irrevocable Trust of 2023 except to the extent of his pecuniary interest therein.
F4	The securities are held by The Francois Grossi Trust, for which Juliana Grossi, the spouse of the reporting person, serves as trustee. The reporting person disclaims beneficial ownership over the shares held by the Francois Grossi Trust except to the extent of his pecuniary interest therein.
F5	The securities are held by The Francois-DuBois Educational Trust, for which the Fiduciary Trust Company of New England serves as trustee. The reporting person disclaims beneficial ownership over the shares held by The Francois-DuBois Educational Trust except to the extent of his pecuniary interest therein.