Alec Machiels - 01 Jan 2026 Form 4 Insider Report for Apellis Pharmaceuticals, Inc. (APLS)

Role: Director
Signature: /s/ David Watson, attorney-in-fact for Alec Machiels
Issuer symbol: APLS
Transactions as of: 01 Jan 2026
Net transactions value: $0
Form type: 4
Filing time: 05 Jan 2026, 16:42:04 UTC
Previous filing: 03 Jan 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Machiels Alec	Director	C/O APELLIS PHARMACEUTICALS, INC., 100 FIFTH AVENUE, 3RD FLOOR, WALTHAM	/s/ David Watson, attorney-in-fact for Alec Machiels	05 Jan 2026	0001496687

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	APLS	Common Stock	Award	$0	+7,961	+2.1%	$0.000000	384,989	01 Jan 2026	Direct	F1
holding	APLS	Common Stock						250,000	01 Jan 2026	Indirect Owner (Bauhaus 1 LLC)	F2
holding	APLS	Common Stock						11,950	01 Jan 2026	Indirect Owner (Owned by Spouse)	F3
holding	APLS	Common Stock						150,000	01 Jan 2026	Indirect Owner (Spouse Trust)	F4

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	APLS	Stock Option (Right to Buy)	Award	$0	+14,684		$0.000000	14,684	01 Jan 2026	Common Stock	14,684	$25.12	Direct	F5

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	This restricted stock unit was granted on January 1, 2026. The restricted stock unit will fully vest on the first anniversary of the date of grant, subject to his continued service as a director, or upon later termination of his service as a director at his election.
F2	The shares are held by Bauhaus 1 LLC, which LLC is held by The Irrevocable Agreement of Trust of Alec Machiels (the "Trust"). The reporting person is the managing member of Bauhaus 1 LLC and the trustee of the Trust.
F3	Owned by spouse.
F4	On September 7, 2021, the reporting person's spouse transferred 150,000 shares of Apellis Pharmaceuticals, Inc. common stock to her trust, of which the reporting person is the trustee.
F5	This option was granted on January 1, 2026. The option vests quarterly on the last day of each quarter from the date of grant, subject to his continued service as a director and expires seven years after the date of grant.