Michael C James - 25 Feb 2026 Form 4 Insider Report for GUIDED THERAPEUTICS INC (GTHP)

Role: Director
Signature: /s/ Michael C James
Issuer symbol: GTHP
Transactions as of: 25 Feb 2026
Net transactions value: $0
Form type: 4
Filing time: 04 Mar 2026, 15:44:48 UTC
Previous filing: 05 Sep 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
JAMES MICHAEL C	Director	5835 PEACHTREE CORNERS EAST, SUITE B, PEACHTREE CORNERS	/s/ Michael C James	04 Mar 2026	0001365831

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	GTHP	Common Stock	Exercise of in-the-money or at-the-money derivative security		+100,000	+18%		653,495	25 Feb 2026	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Shares	Change %	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	GTHP	Warrants	Other	-100,000	-100%	0	25 Feb 2026	Common Stock	100,000	$0.5000	Direct	F1
transaction	GTHP	Warrants	Other	+100,000		100,000	25 Feb 2026	Common Stock	100,000	$0.5000	Direct	F1
transaction	GTHP	Warrants	Other	-100,000	-100%	0	25 Feb 2026	Common Stock	100,000	$0.6500	Direct	F1
transaction	GTHP	Warrants	Other	+100,000	+189%	152,778	25 Feb 2026	Common Stock	100,000	$0.2500	Direct	F1
transaction	GTHP	Warrants	Exercise of in-the-money or at-the-money derivative security	-100,000	-65%	52,778	25 Feb 2026	Common Stock	100,000	$0.2500	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	During February 2026, Mr. James signed an exchange agreement to exchange 100,000 warrants to purchase shares of common stock with an exercise price of $0.65 for 100,000 warrants to purchase shares of common stock for an exercise price of $0.25. The newly exchanged warrants were subsequently exercised upon payment of $25,000. Moreover, as part of the exchange agreement, the expiration date of 4-year 100,000 warrants to purchase shares of common stock with exercise price of $0.50 was extended for an additional year, until September 1, 2027.

Content

During February 2026, Mr. James signed an exchange agreement to exchange 100,000 warrants to purchase shares of common stock with an exercise price of $0.65 for 100,000 warrants to purchase shares of common stock for an exercise price of $0.25. The newly exchanged warrants were subsequently exercised upon payment of $25,000. Moreover, as part of the exchange agreement, the expiration date of 4-year 100,000 warrants to purchase shares of common stock with exercise price of $0.50 was extended for an additional year, until September 1, 2027.