Sarah Gheuens - Dec 23, 2022 Form 4 Insider Report for AGIOS PHARMACEUTICALS, INC. (AGIO)

Role: Chief Medical Officer
Signature: /s/ William Cook, as attorney-in-fact for Sarah Gheuens
Stock symbol: AGIO
Transactions as of: Dec 23, 2022
Transactions value $: -$79,260
Form type: 4
Date filed: 12/28/2022, 03:05 PM
Previous filing: Dec 6, 2022
Next filing: Feb 14, 2023

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	AGIO	Common stock	Options Exercise	$0	+9.38K	+104.02%	$0.00	18.4K	Dec 23, 2022	Direct
transaction	AGIO	Common stock	Tax liability	-$79.3K	-2.78K	-15.13%	$28.48	15.6K	Dec 28, 2022	Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	AGIO	Restricted stock units	Options Exercise	$0	-9.38K	-100%	$0.00^*	0	Dec 23, 2022	Common stock	9.38K		Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.
F2	The restricted stock units were granted on December 23, 2020. The shares underlying the restricted stock units will vest in full on December 23, 2022.