Bruce Car - 06 Jan 2022 Form 4 Insider Report for AGIOS PHARMACEUTICALS, INC. (AGIO)

Role: Chief Scientific Officer
Signature: /s/ William Cook, as Attorney in Fact for Bruce Car
Issuer symbol: AGIO
Transactions as of: 06 Jan 2022
Net transactions value: -$39,259
Form type: 4
Filing time: 10 Jan 2022, 15:06:35 UTC
Next filing: 14 Feb 2022
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	AGIO	Common stock	Options Exercise	$0	+3,437	+48%	$0.000000	10,530	06 Jan 2022	Direct	F1
transaction	AGIO	Common stock	Tax liability	$39,259	-1,205	-11%	$32.58	9,325	06 Jan 2022	Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	AGIO	Restricted stock units	Options Exercise	$0	-3,437	-50%	$0.000000	3,437	06 Jan 2022	Common stock	3,437		Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.
F2	The restricted stock units were granted on January 6, 2020. Beginning on January 6, 2021, the shares underlying the restricted stock units will vest in three equal annual installments.