Jonathan Biller - Dec 3, 2021 Form 4 Insider Report for AGIOS PHARMACEUTICALS, INC. (AGIO)

Role: Chief Financial Officer
Signature: /s/ William Cook, as Attorney in Fact for Jonathan Biller
Stock symbol: AGIO
Transactions as of: Dec 3, 2021
Transactions value $: -$65,406
Form type: 4
Date filed: 12/7/2021, 03:18 PM
Next filing: Feb 14, 2022

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	AGIO	Common stock	Options Exercise	$0	+5.75K	+52.93%	$0.00	16.6K	Dec 3, 2021	Direct	F1, F2
transaction	AGIO	Common stock	Tax liability	-$65.4K	-1.82K	-10.97%	$35.88	14.8K	Dec 3, 2021	Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	AGIO	Restricted stock units	Options Exercise	$0	-5.75K	-50%	$0.00	5.75K	Dec 3, 2021	Common stock	5.75K		Direct	F1, F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.
F2	Includes 830 shares purchased through the Company's employee stock purchase plan.
F3	The restricted stock units were granted on December 3, 2019. Beginning on December 3, 2020, the shares underlying the restricted stock units will vest in three equal annual installments.