Greg Pyszczymuka - 03 Oct 2025 Form 4 Insider Report for AYTU BIOPHARMA, INC (AYTU)

Signature
/s/ Ryan J. Selhorn as attorney-in-fact for Greg Pyszczymuka
Issuer symbol
AYTU
Transactions as of
03 Oct 2025
Net transactions value
$0
Form type
4
Filing time
07 Oct 2025, 16:16:28 UTC
Previous filing
22 May 2025
Next filing
17 Dec 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
PYSZCZYMUKA GREG Chief Commercial Officer C/O AYTU BIOPHARMA, INC., 7900 EAST UNION AVENUE, SUITE 920, DENVER /s/ Ryan J. Selhorn as attorney-in-fact for Greg Pyszczymuka 07 Oct 2025 0001952920

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction AYTU Common Stock Award $0 +12,500 +53% $0.000000 36,102 03 Oct 2025 Direct F1
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 Grant of restricted stock, which vest as follows: 1/3 on October 3, 2026, with the remaining restricted stock vesting in 8 equal quarterly installments beginning January 3, 2027.

Remarks:

Exhibit 24: Power of Attorney