Jarrett T. Disbrow - 09 Jun 2025 Form 4 Insider Report for AYTU BIOPHARMA, INC (AYTU)

Role: Chief Business Officer
Signature: /s/ Jarrett Disbrow
Issuer symbol: AYTU
Transactions as of: 09 Jun 2025
Net transactions value: +$24,999
Form type: 4
Filing time: 10 Jun 2025, 15:06:06 UTC
Previous filing: 08 Nov 2024
Next filing: 07 Oct 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Disbrow Jarrett	Chief Business Officer	C/O AYTU BIOPHARMA, INC., 7900 EAST UNION AVENUE, SUITE 920, DENVER	/s/ Jarrett Disbrow	10 Jun 2025	0001640724

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	AYTU	Common Stock	Purchase	$24,999	+16,666	+130%	$1.50	29,462	09 Jun 2025	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Purchased pursuant to the Issuer's registered offering more particularly described on the Registration Statement on Form S-1, as amended, filed by the Issuer on June 2, 2025.
F2	Total reflects 1-to-20 reverse stock split effected by the Issuer on January 6, 2023.