Greg Pyszczymuka - 31 Mar 2025 Form 4 Insider Report for AYTU BIOPHARMA, INC (AYTU)

Role: Chief Commercial Officer
Signature: /s/ Ryan Selhorn as attorney-in-fact for Greg Pyszczymuka
Issuer symbol: AYTU
Transactions as of: 31 Mar 2025
Net transactions value: $0
Form type: 4
Filing time: 31 Mar 2025, 16:34:24 UTC
Previous filing: 24 Feb 2025
Next filing: 22 May 2025
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	AYTU	Common Shares	Options Exercise		+209	+0.89%		23,602	31 Mar 2025	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	AYTU	Restricted Stock Units	Options Exercise	$0	-209	-100%	$0.000000	0	31 Mar 2025	Common Shares	209		Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Restricted stock units ("RSUs"), each of which represents a contingent right to receive one share of the Issuer's common stock. The RSUs were granted on March 31, 2022, and vest quarterly beginning March 31, 2023 and ending March 31, 2025.