William H. Carson - 02 Sep 2025 Form 4 Insider Report for Annexon, Inc. (ANNX)

Role: Director
Signature: /s/ Jennifer Lew, Attorney-in-Fact
Issuer symbol: ANNX
Transactions as of: 02 Sep 2025
Net transactions value: +$8,600
Form type: 4
Filing time: 04 Sep 2025, 16:30:24 UTC
Previous filing: 01 Aug 2025
Next filing: 02 Oct 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Carson William H.	Director	C/O ANNEXON, INC., 1400 SIERRA POINT PKWY, BLDG C, STE 200, BRISBANE	/s/ Jennifer Lew, Attorney-in-Fact	04 Sep 2025	0001824280

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ANNX	Common Stock	Purchase	$8,600	+4,115	+12%	$2.09	37,945	02 Sep 2025	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id	Content
F1	The transactions reported herein were effected pursuant to the Reporting Person's Rule 10b5-1 trading plan, adopted March 17, 2025.
F2	This transaction was executed in multiple trades in prices ranging from $2.06 to $2.115, inclusive. The price reported in Column 4 above reflects the weighted average purchase price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares purchased at each respective price within the range set forth in this footnote.

Content

The transactions reported herein were effected pursuant to the Reporting Person's Rule 10b5-1 trading plan, adopted March 17, 2025.

This transaction was executed in multiple trades in prices ranging from $2.06 to $2.115, inclusive. The price reported in Column 4 above reflects the weighted average purchase price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares purchased at each respective price within the range set forth in this footnote.