Barry Ticho - 14 Aug 2025 Form 4 Insider Report for Stoke Therapeutics, Inc. (STOK)

Role: CHIEF MEDICAL OFFICER
Signature: /s/ Jonathan Allan, Attorney-in-Fact
Issuer symbol: STOK
Transactions as of: 14 Aug 2025
Net transactions value: $0
Form type: 4
Filing time: 18 Aug 2025, 20:25:58 UTC
Previous filing: 05 Aug 2025
Next filing: 20 Aug 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Ticho Barry	CHIEF MEDICAL OFFICER	C/O STOKE THERAPEUTICS, INC., 45 WIGGINS AVENUE, BEDFORD	/s/ Jonathan Allan, Attorney-in-Fact	18 Aug 2025	0001780088

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	STOK	Common Stock	Options Exercise	$0	+10,000	+60%	$0.000000	26,775	14 Aug 2025	Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	STOK	Performance Stock Units	Award	$0	+20,000		$0.000000	20,000	14 Aug 2025	Common Stock	20,000		Direct	F1, F2, F3
transaction	STOK	Performance Stock Units	Options Exercise	$0	-10,000	-50%	$0.000000	10,000	14 Aug 2025	Common Stock	10,000		Direct	F1, F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Each performance stock unit represents a right to receive one share of the Issuer's common stock.
F2	This award represents a grant of restricted stock units upon the achievement of certain performance criteria as certified by the Issuer's compensation committee on the Transaction Date.
F3	Half the award vests on August 14, 2025 and the remainder shall vest on August 14, 2026, subject to the reporting person's continued service to the Issuer on the relevant vesting date.