| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| 5AM Ventures V, L.P. | 10%+ Owner | C/O 5AM VENTURE MANAGEMENT, LLC, 4 EMBARCADERO CENTER, SUITE 3110, SAN FRANCISCO | 5AM Ventures V, L.P., By: 5AM Partners V, LLC, its General Partner, By /s/ Scott M. Rocklage, Managing Member | 01 Jul 2025 | 0001674324 |
| 5AM Partners V, LLC | 10%+ Owner | C/O 5AM VENTURE MANAGEMENT, LLC, 4 EMBARCADERO CENTER, SUITE 3110, SAN FRANCISCO | 5AM Partners V, LLC, By /s/ Scott M. Rocklage, Managing Member | 01 Jul 2025 | 0001791889 |
| 5AM Opportunities I, L.P. | 10%+ Owner | C/O 5AM VENTURE MANAGEMENT, LLC, 4 EMBARCADERO CENTER, SUITE 3110, SAN FRANCISCO | 5AM Opportunities I, L.P., By: 5AM Opportunities I (GP),LLC, its General Partner, By /s/ Kush Parmar, Managing Member | 01 Jul 2025 | 0001753000 |
| 5AM Opportunities I (GP), LLC | 10%+ Owner | C/O 5AM VENTURE MANAGEMENT, LLC, 4 EMBARCADERO CENTER, SUITE 3110, SAN FRANCISCO | 5AM Opportunities I (GP), LLC, By /s/ Kush Parmar, Managing Member | 01 Jul 2025 | 0001790778 |
| ROCKLAGE SCOTT M | 10%+ Owner | C/O 5AM VENTURE MANAGEMENT, LLC, 4 EMBARCADERO CENTER, SUITE 3110, SAN FRANCISCO | /s/ Scott M. Rocklage | 01 Jul 2025 | 0001219014 |
| Schwab Andrew J. | 10%+ Owner | C/O 5AM VENTURE MANAGEMENT, LLC, 4 EMBARCADERO CENTER, SUITE 3110, SAN FRANCISCO | /s/ Andrew J. Schwab | 01 Jul 2025 | 0001598549 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | TRDA | Common Stock | Sale | $385,129 | -55,735 | -1.7% | $6.91 | 3,220,287 | 27 Jun 2025 | Direct | F1 |
| transaction | TRDA | Common Stock | Sale | $133,121 | -19,265 | -1.7% | $6.91 | 1,113,092 | 27 Jun 2025 | By 5AM Opportunities I, L.P. | F2 |
| transaction | TRDA | Common Stock | Sale | $126,566 | -18,578 | -0.58% | $6.81 | 3,201,709 | 30 Jun 2025 | Direct | F1 |
| transaction | TRDA | Common Stock | Sale | $43,751 | -6,422 | -0.58% | $6.81 | 1,106,670 | 30 Jun 2025 | By 5AM Opportunities I, L.P. | F2 |
| transaction | TRDA | Common Stock | Sale | $132,324 | -18,578 | -0.58% | $7.12 | 3,183,131 | 01 Jul 2025 | Direct | F1 |
| transaction | TRDA | Common Stock | Sale | $45,741 | -6,422 | -0.58% | $7.12 | 1,100,248 | 01 Jul 2025 | By 5AM Opportunities I, L.P. | F2 |
| Id | Content |
|---|---|
| F1 | Shares are held by 5AM Ventures V, L.P. ("5AM V"). 5AM Partners V, LLC ("5AM Partners") is the sole general partner of 5AM V. Dr. Kush Parmar, Andrew J. Schwab and Dr. Scott M. Rocklage are managing members of 5AM Partners and may be deemed to have shared voting and investment power over the shares beneficially owned by 5AM V. Each of 5AM Partners, Mr. Schwab and Dr. Rocklage disclaims beneficial ownership of the shares of Common Stock held by 5AM V, except to the extent of its or his pecuniary interest therein. Dr. Parmar is a director of the Issuer and files separate Section 16 reports. |
| F2 | Shares are held by 5AM Opportunities I, L.P. ("Opportunities"). 5AM Opportunities I (GP), LLC ("Opportunities GP") is the sole general partner of Opportunities. Andrew J. Schwab and Dr. Kush Parmar are managing members of Opportunities GP and may be deemed to have shared voting and investment power over the shares beneficially owned by Opportunities. Each of Opportunities GP and Mr. Schwab disclaims beneficial ownership of the shares of Common Stock held by Opportunities, except to the extent of its or his pecuniary interest therein. Dr. Parmar is a director of the Issuer and files separate Section 16 reports. |