Ariel Hurley - 05 May 2025 Form 4 Insider Report for Blueprint Medicines Corp (BPMC)

Role
PRINCIPAL ACCOUNTING OFFICER
Signature
/s/ Melissa Masse, Attorney-in-Fact
Issuer symbol
BPMC
Transactions as of
05 May 2025
Net transactions value
-$134,853
Form type
4
Filing time
07 May 2025, 16:30:51 UTC
Previous filing
07 Mar 2025
Next filing
21 Jul 2025
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Hurley Ariel PRINCIPAL ACCOUNTING OFFICER C/O BLUEPRINT MEDICINES CORPORATION, 45 SIDNEY STREET, CAMBRIDGE /s/ Melissa Masse, Attorney-in-Fact 07 May 2025 0001769740

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction BPMC Common Stock Options Exercise $148,966 +2,752 +16% $54.13 19,696 05 May 2025 Direct F1
transaction BPMC Common Stock Sale $128,343 -1,252 -6.4% $102.51 18,444 05 May 2025 Direct F1, F2
transaction BPMC Common Stock Sale $144,998 -1,400 -7.6% $103.57 17,044 05 May 2025 Direct F1, F3
transaction BPMC Common Stock Sale $10,478 -100 -0.59% $104.78 16,944 05 May 2025 Direct F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction BPMC Stock Option (Right to Buy) Options Exercise $0 -2,752 -50% $0.000000 2,751 05 May 2025 Common Stock 2,752 $54.13 Direct F1, F4
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 Effected pursuant to a trading plan adopted on September 12, 2024 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.
F2 The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $102.01 to $102.94 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F3 The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $103.23 to $104.06 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F4 This option was granted on March 1, 2020 and is fully exercisable as of the transaction date.