ANDREW KIDD - 17 May 2021 Form 4 Insider Report for Aptinyx Inc.

Role: PRESIDENT & COO
Signature: /s/ Ashish Khanna, Attorney-in-Fact
Issuer symbol: N/A
Transactions as of: 17 May 2021
Net transactions value: -$96,368
Form type: 4
Filing time: 19 May 2021, 18:48:49 UTC
Next filing: 07 Dec 2021
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	APTX	Common Stock	Options Exercise	$0	+130,000	+1423%	$0.000000	139,133	17 May 2021	Direct	F1
transaction	APTX	Common Stock	Tax liability	$96,368	-38,090	-27%	$2.53^*	101,043	17 May 2021	Direct	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	APTX	Restricted Stock Units	Options Exercise	$0	-130,000	-100%	$0.000000^*	0	17 May 2021	Common Stock	130,000		Direct	F3, F4

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents shares of Common Stock issued to the reporting person upon settlement of the RSUs on May 17, 2021, the business day immediately following May 16, 2021, the date that the RSUs became fully vested.
F2	Represents the number of shares of Common Stock that have been withheld by the issuer to satisfy its income tax withholding and remittance obligations in connection with the net settlement of the RSUs and does not represent a sale by the reporting person.
F3	Each restricted stock unit represents a contingent right to receive one share of common stock.
F4	The restricted stock units vest on May 16, 2021, subject to the Reporting Person's continued service. The underlying vested shares settled on May 17, 2021, the business day immediately following May 16, 2021.