| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Schaeffer Orlov S Nicole | Chief People Strategy Officer | 700 US HIGHWAY 202/206, BRIDGEWATER | /s/ S. Nicole Schaeffer, by Michael A. Smith as Attorney-in-fact | 18 Aug 2025 | 0001401017 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | INSM | Common Stock | Sale | $449,830 | -3,554 | -4% | $126.57 | 86,210 | 14 Aug 2025 | Direct | F1, F2 |
| transaction | INSM | Common Stock | Sale | $733,822 | -5,746 | -6.7% | $127.71 | 80,464 | 14 Aug 2025 | Direct | F3 |
| transaction | INSM | Common Stock | Sale | $89,712 | -700 | -0.87% | $128.16 | 79,764 | 14 Aug 2025 | Direct | F4 |
| Id | Content |
|---|---|
| F1 | This is the weighted average sales price representing 3,554 shares sold at prices ranging from $126.01 to $126.94 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request. |
| F2 | Includes 357 shares acquired through the Company's 2018 Employee Stock Purchase Plan. |
| F3 | This is the weighted average sales price representing 5,746 shares sold at prices ranging from $127.08 to $128.00 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request. |
| F4 | This is the weighted average sales price representing 700 shares sold at prices ranging from $128.10 to $128.24 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request. |
Exhibit List - Exhibit 24 - Power of Attorney