| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Pignagnoli Agosti Marcello | Global Bus. Devel. Officer | 300 MASSACHUSETTS AVE., CAMBRIDGE | /s/ Max Heuer, by power of attorney, for Marcello Agosti | 18 Mar 2026 | 0001977817 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| holding | TAK | American Depositary Shares | 144,608 | 18 Mar 2026 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | Includes 53,850 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest on the following schedule: July 1, 2026 (24,510 shares), July 1, 2027 (19,798 shares) and July 1, 2028 (9,542 shares). |
Exhibit 24 Power of Attorney