Caley Castelein - 15 Oct 2025 Form 4 Insider Report for Tourmaline Bio, Inc. (TRML)

Role: Director
Signature: /s/ Brad Middlekauff, Attorney-in-Fact
Issuer symbol: TRML
Transactions as of: 15 Oct 2025
Net transactions value: $0
Form type: 4
Filing time: 17 Oct 2025, 17:50:10 UTC
Previous filing: 16 Jun 2025
Next filing: 28 Oct 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Castelein Caley	Director	C/O TOURMALINE BIO, INC., 27 WEST 24TH STREET, SUITE 702, NEW YORK	/s/ Brad Middlekauff, Attorney-in-Fact	17 Oct 2025	0001355758

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	TRML	Common Stock	Gift	$0	-522	-0.1%	$0.000000	515,997	15 Oct 2025	Direct
holding	TRML	Common Stock						431,939	15 Oct 2025	By KVP Capital, LP	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Gives effect to in-kind distribution of shares by KVP Capital, LP ("KVP") to its limited partner for no consideration, subsequent to the Reporting Person's most recent filing, which represented a change in the form of the Reporting Person's ownership that was not required to be reported under Section 16.
F2	These shares are held by KVP. The Reporting Person is the Managing Member of KVP Capital GP, LLC, the General Partner of KVP and, as such, has sole voting and investment power with respect to the shares held by KVP. The Reporting Person disclaims beneficial ownership of the shares held by KVP except to the extent of his pecuniary interest therein and this report is not an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.

Content

Gives effect to in-kind distribution of shares by KVP Capital, LP ("KVP") to its limited partner for no consideration, subsequent to the Reporting Person's most recent filing, which represented a change in the form of the Reporting Person's ownership that was not required to be reported under Section 16.

These shares are held by KVP. The Reporting Person is the Managing Member of KVP Capital GP, LLC, the General Partner of KVP and, as such, has sole voting and investment power with respect to the shares held by KVP. The Reporting Person disclaims beneficial ownership of the shares held by KVP except to the extent of his pecuniary interest therein and this report is not an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.