| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Krishnan Suma | President, R&D, Director, 10%+ Owner | C/O KRYSTAL BIOTECH, INC., 2100 WHARTON STREET, SUITE 701, PITTSBURGH | /s/ Suma M. Krishnan | 16 Jul 2025 | 0001298711 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | KRYS | Common Stock | Sale | $2,004,125 | -13,335 | -0.92% | $150.29 | 1,443,376 | 14 Jul 2025 | Direct | F1, F2 |
| transaction | KRYS | Common Stock | Sale | $15,100 | -100 | -0.01% | $151.00 | 1,443,276 | 14 Jul 2025 | Direct | F1, F3 |
| transaction | KRYS | Common Stock | Sale | $336,929 | -2,236 | -0.15% | $150.68 | 1,441,040 | 15 Jul 2025 | Direct | F1, F4 |
| transaction | KRYS | Common Stock | Sale | $121,432 | -800 | -0.06% | $151.79 | 1,440,240 | 15 Jul 2025 | Direct | F1, F3 |
| transaction | KRYS | Common Stock | Sale | $229,350 | -1,529 | -0.11% | $150.00 | 1,438,711 | 16 Jul 2025 | Direct | F1, F3 |
| transaction | KRYS | Common Stock | Sale | $2,014,015 | -13,400 | -0.88% | $150.30 | 1,512,529 | 14 Jul 2025 | By Spouse | F6, F7, F8 |
| transaction | KRYS | Common Stock | Sale | $329,089 | -2,184 | -0.14% | $150.68 | 1,510,345 | 15 Jul 2025 | By Spouse | F6, F8, F9 |
| transaction | KRYS | Common Stock | Sale | $136,611 | -900 | -0.06% | $151.79 | 1,509,445 | 15 Jul 2025 | By Spouse | F3, F6, F8 |
| transaction | KRYS | Common Stock | Sale | $208,350 | -1,389 | -0.09% | $150.00 | 1,508,056 | 16 Jul 2025 | By Spouse | F3, F6, F8 |
| holding | KRYS | Common Stock | 90,000 | 14 Jul 2025 | By SMK Trust | ||||||
| holding | KRYS | Common Stock | 50,000 | 14 Jul 2025 | By Krishnan Family Trust | F5 |
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
| Id | Content |
|---|---|
| F1 | The sales reported were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan started on September 12, 2024, and contemplated quarterly sales of 25,000 shares of Common Stock. The Rule 10b5-1 trading plan has reached the maximum number of shares to be sold under such plan and has terminated. |
| F2 | The transaction was executed in multiple trades ranging from $150.00 to $150.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein. |
| F3 | The transaction was executed in one trade. |
| F4 | The transaction was executed in multiple trades ranging from $150.21 to $151.18. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein. |
| F5 | Directly beneficially owned by the Krishnan Family Trust. The reporting person and her spouse are each joint beneficial owners of the trust with joint voting and investment control. |
| F6 | The sales reported were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person's spouse, Krish S. Krishnan. The Rule 10b5-1 trading plan started on September 12, 2024, and contemplated quarterly sales of 25,000 shares of Common Stock. The Rule 10b5-1 trading plan has reached the maximum number of shares to be sold under such plan and has terminated. |
| F7 | The transaction was executed in multiple trades ranging from $150.00 to $150.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein. |
| F8 | Directly beneficially owned by Krish S. Krishnan, the spouse of the Reporting Person. |
| F9 | The transaction was executed in multiple trades ranging from $150.21 to $151.00. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein. |