Joseph J. Larosa - 05 Dec 2025 Form 4 Insider Report for REGENERON PHARMACEUTICALS, INC. (REGN)

Role: EVP General Counsel and Secret
Signature: /s/ Joseph LaRosa
Issuer symbol: REGN
Transactions as of: 05 Dec 2025
Net transactions value: -$995,264
Form type: 4
Filing time: 09 Dec 2025, 16:09:43 UTC
Previous filing: 24 Nov 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
LAROSA JOSEPH J	EVP General Counsel and Secret	777 OLD SAW MILL RIVER ROAD, TARRYTOWN	/s/ Joseph LaRosa	09 Dec 2025	0001238303

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	REGN	Common Stock	Award	$0	+2,476	+8.7%	$0.000000	30,913	05 Dec 2025	Direct	F1
transaction	REGN	Common Stock	Tax liability	$995,264	-1,396	-4.5%	$712.94	29,517	08 Dec 2025	Direct
holding	REGN	Common Stock						3,402	05 Dec 2025	By 2024 GRAT
holding	REGN	Common Stock						9,000	05 Dec 2025	By 2025 GRAT
holding	REGN	Common Stock						396	05 Dec 2025	By 401(k) Plan

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	REGN	Non-Qualified Stock Option (right to buy)	Award	$0	+12,210		$0.000000	12,210	05 Dec 2025	Common Stock	12,210	$726.71	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Award of Restricted Stock under the Second Amended and Restated 2014 Long-Term Incentive Plan that vests 50% on December 5, 2027 and 50% on December 5, 2029.
F2	The stock option award vests in four equal annual installments, commencing one year after the date of grant.