| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | Director | 200 BERKELEY STREET, 18TH FLOOR, BOSTON | /s/ Peter Kolchinsky, Manager of RA Capital Management, L.P. | 20 Feb 2026 | 0001346824 |
| RA Capital Healthcare Fund LP | Director | 200 BERKELEY STREET, 18TH FLOOR, BOSTON | /s/ Peter Kolchinsky, Manager of RA Capital Healthcare Fund GP, LLC the General Partner of RA Capital Healthcare Fund, L.P. | 20 Feb 2026 | 0001315082 |
| RA Capital Nexus Fund III, L.P. | Director | 200 BERKELEY STREET, 18TH FLOOR, BOSTON | /s/ Peter Kolchinsky, Manager of RA Capital Nexus Fund III GP, LLC the General Partner of RA Capital Nexus Fund III, L.P. | 20 Feb 2026 | 0001883840 |
| Kolchinsky Peter | Director | C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON | /s/ Peter Kolchinsky, individually | 20 Feb 2026 | 0001384859 |
| Shah Rajeev M. | Director | C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON | /s/ Rajeev Shah, individually | 20 Feb 2026 | 0001619841 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | MLYS | Common Stock | Award | $0 | +6,200 | $0.000000 | 6,200 | 19 Feb 2026 | See footnotes | F1, F2, F3 | |
| holding | MLYS | Common Stock | 5,456,521 | 19 Feb 2026 | See footnotes | F2, F4 | |||||
| holding | MLYS | Common Stock | 1,867,229 | 19 Feb 2026 | See Footnote | F2, F5 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | MLYS | Stock Option (Right to Buy) | Award | $0 | +8,300 | $0.000000 | 8,300 | 19 Feb 2026 | Common Stock | 8,300 | $28.06 | See Footnote | F2, F3, F6 |
| Id | Content |
|---|---|
| F1 | Restricted Stock Units (RSUs) are granted to Dr. Derek DiRocco for no additional cash consideration, each of which represents a contingent right to receive one share of common stock upon vesting of these RSUs in one annual installment following the date of grant. |
| F2 | RA Capital Management, L.P. (the "Adviser") is the investment manager for RA Capital Healthcare Fund, L.P. (the "Fund") and RA Capital Nexus III Fund, L.P. (the "Nexus Fund III"). The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, the Fund, the Nexus Fund III, Dr. Kolchinsky and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein. |
| F3 | Derek DiRocco is a Partner of the Adviser who serves on the Issuer's board of directors. Under Dr. DiRocco's arrangement with the Adviser, Dr. DiRocco holds the RSUs and the options for the benefit of the Fund and the Nexus Fund III. Dr. DiRocco is obligated to turn over to the Adviser any net cash or stock received upon settlement of the RSUs or exercise of the options, as applicable, which will offset advisory fees owed by the Fund and the Nexus Fund III to the Adviser. The Reporting Persons therefore disclaim beneficial ownership of the option and underlying common stock. |
| F4 | Held directly by the Fund. |
| F5 | Held directly by Nexus Fund III. |
| F6 | The stock option vests in 12 substantially equal monthly installments following the date of grant. |
Dr. Derek DiRocco, a Partner of the Adviser, serves on the Issuer's board of directors.