Srinivas Akkaraju - 22 Dec 2025 Form 4 Insider Report for Kalaris Therapeutics, Inc. (KLRS)

Role: Director, 10%+ Owner
Signature: Samsara Opportunity Fund, L.P., By Samsara Opportunity Fund GP, LLC, its General Partner, By /s/ Srinivas Akkaraju, Managing Member
Issuer symbol: KLRS
Transactions as of: 22 Dec 2025
Net transactions value: +$15,000,000
Form type: 4
Filing time: 22 Dec 2025, 16:15:40 UTC
Previous filing: 17 Feb 2026
Next filing: 13 Jan 2026
SEC: View on sec.gov

Reporting Owners (3)

Name	Relationship	Address	Signature	Signature date	CIK
AKKARAJU SRINIVAS	Director, 10%+ Owner	C/O SAMSARA BIOCAPITAL, LLC, 628 MIDDLEFIELD ROAD, PALO ALTO	Samsara Opportunity Fund, L.P., By Samsara Opportunity Fund GP, LLC, its General Partner, By /s/ Srinivas Akkaraju, Managing Member	22 Dec 2025	0001253170
Samsara Opportunity Fund, L.P.	10%+ Owner	C/O SAMSARA BIOCAPITAL, LLC, 628 MIDDLEFIELD ROAD, PALO ALTO	Samsara Opportunity Fund GP, LLC, By /s/ Srinivas Akkaraju, Managing Member	22 Dec 2025	0002086193
Samsara Opportunity Fund GP, LLC	10%+ Owner	C/O SAMSARA BIOCAPITAL, LLC, 628 MIDDLEFIELD ROAD, PALO ALTO	/s/ Srinivas Akkaraju	22 Dec 2025	0002086456

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	KLRS	Common Stock	Award	$15,000,000	+1,500,000		$10.00	1,500,000	22 Dec 2025	By Samsara Opportunity Fund, L.P.	F1
holding	KLRS	Common Stock						11,448,081	22 Dec 2025	By Samsara BioCapital, L.P.	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Securities are directly held by Samsara Opportunity Fund, L.P. ("Samsara Opportunity Fund"). Samsara Opportunity Fund GP, LLC ("Samsara Opportunity GP") is the general partner of Samsara Opportunity Fund and may be deemed to beneficially own the securities held by Samsara Opportunity Fund. Samsara Opportunity GP and Dr. Akkaraju have voting and investment power over the securities held by Samsara Opportunity Fund and, accordingly, may be deemed to beneficially own the securities held by Samsara Opportunity Fund. Each of the Reporting Persons disclaims beneficial ownership in these securities except to the extent of his or its respective pecuniary interest therein.
F2	Securities are directly held by Samsara BioCapital L.P. ("Samsara LP"). Samsara BioCapital GP, LLC is the general partner of Samsara LP and may be deemed to beneficially own the securities held by Samsara LP. Dr. Akkaraju has voting and investment power over the securities held by Samsara LP and, accordingly, may be deemed to beneficially own the securities held by Samsara LP. Dr. Akkaraju disclaims beneficial ownership in these securities except to the extent of his pecuniary interest therein.

Content

Securities are directly held by Samsara Opportunity Fund, L.P. ("Samsara Opportunity Fund"). Samsara Opportunity Fund GP, LLC ("Samsara Opportunity GP") is the general partner of Samsara Opportunity Fund and may be deemed to beneficially own the securities held by Samsara Opportunity Fund. Samsara Opportunity GP and Dr. Akkaraju have voting and investment power over the securities held by Samsara Opportunity Fund and, accordingly, may be deemed to beneficially own the securities held by Samsara Opportunity Fund. Each of the Reporting Persons disclaims beneficial ownership in these securities except to the extent of his or its respective pecuniary interest therein.

Securities are directly held by Samsara BioCapital L.P. ("Samsara LP"). Samsara BioCapital GP, LLC is the general partner of Samsara LP and may be deemed to beneficially own the securities held by Samsara LP. Dr. Akkaraju has voting and investment power over the securities held by Samsara LP and, accordingly, may be deemed to beneficially own the securities held by Samsara LP. Dr. Akkaraju disclaims beneficial ownership in these securities except to the extent of his pecuniary interest therein.