| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | Director, 10%+ Owner | 200 BERKELEY STREET 18TH FLOOR, BOSTON | /s/ Peter Kolchinsky, Manager of RA Capital Management, L.P. | 19 Dec 2025 | 0001346824 |
| RA Capital Healthcare Fund LP | Director, 10%+ Owner | 200 BERKELEY STREET, 18TH FLOOR, BOSTON | /s/ Peter Kolchinsky, Manager of RA Capital Healthcare GP, LLC, the General Partner of RA Capital Healthcare Fund, L.P. | 19 Dec 2025 | 0001315082 |
| Kolchinsky Peter | Director, 10%+ Owner | C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON | /s/ Peter Kolchinsky, individually | 19 Dec 2025 | 0001384859 |
| Shah Rajeev M. | Director, 10%+ Owner | C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON | /s/ Rajeev Shah, individually | 19 Dec 2025 | 0001619841 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VOR | Common Stock | Award | $49,999,990 | -4,625,346 | -46% | $10.81 | 5,404,998 | 18 Dec 2025 | See footnotes | F1, F2 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VOR | Stock Option (Right to Buy) | Award | $0 | +3,000 | $0.000000 | 3,000 | 18 Dec 2025 | Common Stock | 3,000 | $12.80 | See Footnotes | F1, F3, F4 |
| Id | Content |
|---|---|
| F1 | RA Capital Management, L.P. (the "Adviser") is the investment manager for RA Capital Healthcare Fund, L.P. (the "Fund"). The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. Each of the Adviser, the Adviser GP, the Fund, Dr. Kolchinsky and Mr. Shah disclaims beneficial ownership of any of the reported securities, except to the extent of its or his respective pecuniary interest therein. |
| F2 | Held directly by the Fund. |
| F3 | This option was granted to Dr. Andrew Levin pursuant to the Issuer's non-employee director compensation policy. The shares shall vest and become exercisable in a series of 36 successive equal monthly installments beginning on December 18, 2025, in each case subject to Dr. Levin's continued service as of each such date. |
| F4 | Under Dr. Levin's arrangement with the Adviser, Dr. Levin holds the option for the benefit of the Fund. Dr. Levin is obligated to turn over to the Adviser any net cash or stock received upon exercise of the option, which will offset advisory fees owed by the Fund to the Adviser. The Reporting Persons therefore disclaim beneficial ownership of the option and underlying common stock. |
Dr. Andrew Levin, a Partner and Managing Director of the Adviser, serves on the Issuer's board of directors.