GEORGE YANCOPOULOS - 09 Dec 2025 Form 4 Insider Report for REGENERON PHARMACEUTICALS, INC. (REGN)

Signature
/s/ George D. Yancopoulos
Issuer symbol
REGN
Transactions as of
09 Dec 2025
Net transactions value
-$10,930,239
Form type
4
Filing time
11 Dec 2025, 16:27:23 UTC
Previous filing
12 Jun 2024
Next filing
05 Jan 2026

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
YANCOPOULOS GEORGE Bd. Co-Chair, President & CSO, Director 777 OLD SAW MILL RIVER ROAD, TARRYTOWN /s/ George D. Yancopoulos 11 Dec 2025 0001226690

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction REGN Common Stock Options Exercise $81,580,691 +146,815 +50% $555.67 442,334 09 Dec 2025 Direct
transaction REGN Common Stock Tax liability $92,510,930 -131,874 -30% $701.51 310,460 09 Dec 2025 Direct
holding REGN Common Stock 71,487 09 Dec 2025 By 2024 GRAT
holding REGN Common Stock 200,000 09 Dec 2025 By 2025 GRAT
holding REGN Common Stock 200,000 09 Dec 2025 By 2025 GRAT II
holding REGN Common Stock 5,962 09 Dec 2025 By 401(k) Plan
holding REGN Common Stock 180,000 09 Dec 2025 By Trust for Chldn. F1
holding REGN Common Stock 101,988 09 Dec 2025 by 2024 GRAT II
holding REGN Common Stock 56,048 09 Dec 2025 by Children

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction REGN Non-Qualified Stock Option (right to buy) Options Exercise $0 -146,815 -100% $0.000000 0 09 Dec 2025 Common Stock 146,815 $555.67 Direct F2
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 As investment trustee of trusts for the benefit of the reporting person's children.
F2 The stock option award vested in four equal annual installments, commencing one year after the date of grant.