Randal J. Kirk - 22 Dec 2025 Form 4 Insider Report for PRECIGEN, INC. (PGEN)

Role: Director, 10%+ Owner
Signature: /s/ Randal J. Kirk
Issuer symbol: PGEN
Transactions as of: 22 Dec 2025
Net transactions value: -$7,942,150
Form type: 4
Filing time: 22 Dec 2025, 20:48:33 UTC
Previous filing: 21 Nov 2025
Next filing: 12 Mar 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
KIRK RANDAL J	Director, 10%+ Owner	C/O THIRD SECURITY, LLC, 1881 GROVE AVENUE, RADFORD	/s/ Randal J. Kirk	22 Dec 2025	0001091823

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	PGEN	Common Stock	Sale	$2,320,397	-555,119	-0.68%	$4.18	81,609,648	22 Dec 2025	by R.J. Kirk DOT	F1, F2
transaction	PGEN	Common Stock	Sale	$53,960	-12,909	-2.6%	$4.18	477,492	22 Dec 2025	by JPK 2008	F1, F2
transaction	PGEN	Common Stock	Sale	$394,345	-94,341	-2.5%	$4.18	3,609,057	22 Dec 2025	by JPK 2009	F1, F2
transaction	PGEN	Common Stock	Sale	$161,887	-38,729	-2.3%	$4.18	1,615,634	22 Dec 2025	by JPK 2012	F1, F2
transaction	PGEN	Common Stock	Sale	$53,960	-12,909	-2.6%	$4.18	476,529	22 Dec 2025	by MGK 2008	F1, F2
transaction	PGEN	Common Stock	Sale	$665,962	-159,321	-4%	$4.18	3,785,116	22 Dec 2025	by MGK 2009	F1, F2
transaction	PGEN	Common Stock	Sale	$178,494	-42,702	-2.6%	$4.18	1,594,338	22 Dec 2025	by MGK 2011	F1, F2
transaction	PGEN	Common Stock	Sale	$49,813	-11,917	-2.1%	$4.18	566,162	22 Dec 2025	by ZSK 2008	F1, F2
transaction	PGEN	Common Stock	Sale	$41,512	-9,931	-2.8%	$4.18	341,189	22 Dec 2025	by ZSK 2009	F1, F2
transaction	PGEN	Common Stock	Sale	$24,904	-5,958	-1.3%	$4.18	447,773	22 Dec 2025	by Kellie L. Banks LTT	F1, F2
transaction	PGEN	Common Stock	Sale	$3,996,916	-956,200	-17%	$4.18	4,598,044	22 Dec 2025	by Kapital Joe	F1, F2
holding	PGEN	Common Stock						1,403	22 Dec 2025	by Lotus	F2
holding	PGEN	Common Stock						6,085,471	22 Dec 2025	by Third Security	F2
holding	PGEN	Common Stock						1,096,686	22 Dec 2025	by Parkview 2020	F2
holding	PGEN	Common Stock						14,597,161	22 Dec 2025	by Sunset 2020	F2
holding	PGEN	Common Stock						1,144,481	22 Dec 2025	by Spouse

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.1800 to $4.1900, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4.
F2	Randal J. Kirk controls each of R.J. Kirk Declaration of Trust ("R.J. Kirk DOT"), JPK 2008 LLC ("JPK 2008"), JPK 2009 LLC ("JPK 2009"), JPK 2012 LLC ("JPK 2012"), MGK 2008 LLC ("MGK 2008"), MGK 2009 LLC ("MGK 2009"), MGK 2011 LLC ("MGK 2011"), ZSK 2008 LLC ("ZSK 2008"), ZSK 2009 LLC ("ZSK 2009"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Kapital Joe, LLC ("Kapital Joe"), Lotus Capital (2000) Company, Inc. ("Lotus"), Third Security, LLC ("Third Security"), Parkview 2020 Limited Partnership ("Parkview 2020") and Sunset 2020 LLC ("Sunset 2020"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

Content

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.1800 to $4.1900, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4.

Randal J. Kirk controls each of R.J. Kirk Declaration of Trust ("R.J. Kirk DOT"), JPK 2008 LLC ("JPK 2008"), JPK 2009 LLC ("JPK 2009"), JPK 2012 LLC ("JPK 2012"), MGK 2008 LLC ("MGK 2008"), MGK 2009 LLC ("MGK 2009"), MGK 2011 LLC ("MGK 2011"), ZSK 2008 LLC ("ZSK 2008"), ZSK 2009 LLC ("ZSK 2009"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Kapital Joe, LLC ("Kapital Joe"), Lotus Capital (2000) Company, Inc. ("Lotus"), Third Security, LLC ("Third Security"), Parkview 2020 Limited Partnership ("Parkview 2020") and Sunset 2020 LLC ("Sunset 2020"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.