Mark William Lowdell - 01 Dec 2025 Form 4 Insider Report for Inmune Bio, Inc. (INMB)

Role: Chief Scientific Officer
Signature: /s/ Mark William Lowdell
Issuer symbol: INMB
Transactions as of: 01 Dec 2025
Net transactions value: $0
Form type: 4
Filing time: 02 Dec 2025, 16:43:26 UTC
Previous filing: 18 Nov 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Lowdell Mark William	Chief Scientific Officer	C/O INMUNE BIO INC., 225 NE MIZNER BLVD., SUITE 640, BOCA RATON	/s/ Mark William Lowdell	02 Dec 2025	0001767037

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	INMB	Option (right to buy)	Award	$0	+600,000		$0.000000	600,000	01 Dec 2025	Common Stock	600,000	$1.48	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Granted pursuant to the Issuer's Second Amended and Restated 2021 Stock Incentive Plan. One-fourth (1/4) of the option will vest 12 months from the date of grant and thereafter the remaining unvested option will become vested and exercisable pro rata on a monthly basis over three (3) years (1/36 per month) until the option is 100% vested which shall occur on the four-year anniversary of the date of grant.

Content

Granted pursuant to the Issuer's Second Amended and Restated 2021 Stock Incentive Plan. One-fourth (1/4) of the option will vest 12 months from the date of grant and thereafter the remaining unvested option will become vested and exercisable pro rata on a monthly basis over three (3) years (1/36 per month) until the option is 100% vested which shall occur on the four-year anniversary of the date of grant.