| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Smith Ryan Lewis | Director | 3000 EL CAMINO REAL, BLDG. 4,, SUITE 200, PALO ALTO | /s/ Ryan Smith | 11 Aug 2025 | 0001619129 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| holding | ATNF | Common Stock | 167,181 | 08 Aug 2025 | Direct |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ATNF | Non-Qualified Stock Option (right to buy) | Award | $0 | +771,044 | $0.000000 | 771,044 | 08 Aug 2025 | Common Stock | 771,044 | $3.01 | Direct | F1, F2 |
| Id | Content |
|---|---|
| F1 | The options were granted under the 2025 Second Supplemental Option Plan of the Issuer. The options vested immediately, but are not exercisable until stockholder approval of the 2025 Second Supplemental Option Plan is received. If stockholder approval is not received prior to August 8, 2026, the options will be cancelled. |
| F2 | Issued to the Reporting Person in consideration for services rendered and agreed to be rendered to the Issuer as a director of the Issuer. |