| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ITRM | Ordinary Shares | Options Exercise | +5.48K | +61.79% | 14.3K | Oct 1, 2023 | Direct | F1 | ||
| holding | ITRM | Ordinary Shares | 71.4K | Oct 1, 2023 | By New Leaf Ventures III, L.P. | F2 | |||||
| holding | ITRM | Ordinary Shares | 25.6K | Oct 1, 2023 | By New Leaf Biopharma Opportunities II, L.P. | F3 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ITRM | Restricted Share Units | Options Exercise | $0 | -5.48K | -100% | $0.00* | 0 | Oct 1, 2023 | Ordinary Shares | 5.48K | Direct | F1, F4 |
| Id | Content |
|---|---|
| F1 | Restricted share units ("RSUs") converted into ordinary shares on a one-for-one basis upon vesting of the RSUs. |
| F2 | These shares are held directly by New Leaf Ventures III, L.P. ("NLV-III"). New Leaf Venture Associates III, L.P. ("NLVA-III LP") is the general partner of NLV-III and New Leaf Venture Management III, L.L.C. ("NLVM-III LLC") is the general partner of NLVA-III LP, and each of NLVA-III LP and NLVM-III LLC may be deemed to have sole voting, investment and dispositive power with respect to the shares held by NLV-III. The reporting person, a member of the Issuer's Board of Directors, is a managing director of NLVM-III LLC and, in his capacity as a managing director, may be deemed to have shared voting, investment and dispositive power with respect to the shares held by NLV-III. The reporting person disclaims Section 16 beneficial ownership of the securities held by NLV-III, except to the extent of his pecuniary interest therein, if any. |
| F3 | These shares are held directly by New Leaf Biopharma Opportunities II, L.P. ("NBPO-II"). New Leaf BPO Associates II, L.P. ("NBPO-IIA") is the general partner of NBPO-II and New Leaf BPO Management II, L.L.C. ("NBPO-IIM") is the general partner of NBPO-IIA, and each of NBPO-IIA and NBPO-IIM may be deemed to have sole voting, investment and dispositive power with respect to the shares held by NBPO-II. The reporting person, a member of the Issuer's Board of Directors, is a managing director of NBPO-IIM and, in his capacity as a managing director, may be deemed to have shared voting, investment and dispositive power with respect to the shares held by NBPO-II. The reporting person disclaims Section 16 beneficial ownership of the securities held by NBPO-II, except to the extent of his pecuniary interest therein, if any. |
| F4 | On December 23, 2022, the reporting person was granted an award of 5,479 RSUs, which vested in full on October 1, 2023. |