Siddarth Subramony - May 31, 2023 Form 4 Insider Report for Tyra Biosciences, Inc. (TYRA)

Role: Director, 10%+ Owner
Signature: /s/ Ali D. Fawaz, Attorney-in-Fact
Stock symbol: TYRA
Transactions as of: May 31, 2023
Transactions value $: $0
Form type: 4
Date filed: 6/2/2023, 04:31 PM
Previous filing: Jun 15, 2022
Next filing: May 31, 2024

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	TYRA	Stock Option (Right to Buy)	Award	$0	+14.5K		$0.00	14.5K	May 31, 2023	Common Stock	14.5K	$14.47	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The option was granted pursuant to the Issuer's Non-Employee Director Compensation Program. 1/12th of the total number of shares of common stock subject to the option vest monthly following May 31, 2023, the date of grant. In the event the next occurring annual meeting of the Issuer's stockholders occurs prior to the first anniversary of the date of grant, any remaining unvested portion of the option will vest on the date of such annual meeting of the Issuer's stockholders, subject to the Reporting Person's continuous service to the Issuer through each vesting date.
F2	These securities are owned directly by the Reporting Person, who may be deemed to be a member of a "group" for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended, consisting of (i) Boxer Capital, LLC, (ii) Boxer Asset Management Inc., (iii) MVA Investors, LLC, (iv) Joseph C. Lewis, and (v) the Reporting Person (collectively, the "Boxer Group"). Each member of the Boxer Group other than the Reporting Person disclaims beneficial ownership of these securities to the extent it does not have a pecuniary interest therein.

Content

The option was granted pursuant to the Issuer's Non-Employee Director Compensation Program. 1/12th of the total number of shares of common stock subject to the option vest monthly following May 31, 2023, the date of grant. In the event the next occurring annual meeting of the Issuer's stockholders occurs prior to the first anniversary of the date of grant, any remaining unvested portion of the option will vest on the date of such annual meeting of the Issuer's stockholders, subject to the Reporting Person's continuous service to the Issuer through each vesting date.

These securities are owned directly by the Reporting Person, who may be deemed to be a member of a "group" for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended, consisting of (i) Boxer Capital, LLC, (ii) Boxer Asset Management Inc., (iii) MVA Investors, LLC, (iv) Joseph C. Lewis, and (v) the Reporting Person (collectively, the "Boxer Group"). Each member of the Boxer Group other than the Reporting Person disclaims beneficial ownership of these securities to the extent it does not have a pecuniary interest therein.