(HRTX)

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	HRTX	Employee Stock Option (Right to Buy)	Award	$0	+3,000,000	$0.000000	3,000,000	03 Apr 2023	Common Stock	3,000,000	$1.78	Direct	F1
transaction	HRTX	Restricted Stock Units	Award	$0	+250,000	$0.000000	250,000	03 Apr 2023	Common Stock	250,000	$0.000000	Direct	F2
transaction	HRTX	Employee Performance Stock Option (Right to Buy)	Award	$0	+4,250,000	$0.000000	4,250,000	03 Apr 2023	Common Stock	4,250,000	$1.78	Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Id	Content
F1	The stock option vests and becomes exercisable with respect to 750,000 shares on the first anniversary of the date of grant, followed by 2,250,000 shares vesting ratably each month over the subsequent three years, such that 3,000,000 options will be fully vested on the four-year anniversary of the date of grant, subject to the Reporting Person's continued service to the Issuer through the vesting date.
F2	The restricted stock units vest in four equal annual installments beginning one year after the date of grant, subject to the Reporting Person's continued service to the Issuer through the vesting date.
F3	The stock option vests and becomes exercisable with respect to escalating portions of the option grant upon the Issuer's stock price reaching certain pre-established levels ranging from $4.50 to $9.00 per share, subject to the Reporting Person's continued service to the Issuer through the vesting date.