| Id | Content |
|---|---|
| F1 | Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1. |
| F2 | Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price. |
| F3 | Open market sales reported on this line occurred at a weighted average price of $295.79 (range $295.31 to $296.12). |
| F4 | Open market sales reported on this line occurred at a weighted average price of $296.85 (range $296.42 to $297.37). |
| F5 | Open market sales reported on this line occurred at a weighted average price of $297.97 (range $297.50 to $298.35). |
| F6 | Open market sales reported on this line occurred at a weighted average price of $299.08 (range $298.71 to $299.54). |
| F7 | Open market sales reported on this line occurred at a weighted average price of $300.11 (range $299.76 to $300.70). |
| F8 | Open market sales reported on this line occurred at a weighted average price of $301.02 (range $300.79 to $301.22). |