Gary J. Nabel - Jun 22, 2022 Form 4 Insider Report for OPKO HEALTH, INC. (OPK)

Role: Chief Innovation Officer, Director
Signature: Steven D. Rubin, Attorney-in-Fact
Stock symbol: OPK
Transactions as of: Jun 22, 2022
Transactions value $: $597,393
Form type: 4
Date filed: 6/24/2022, 07:52 PM
Previous filing: Jun 16, 2022
Next filing: Aug 10, 2022

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	OPK	Common Stock	Purchase	$3.72K	+1.49K	+0.01%	$2.50	19.8M	Jun 22, 2022	Held by the GJN 2021 TRUST	F1
transaction	OPK	Common Stock	Purchase	$163K	+65.3K	+0.33%	$2.50	19.8M	Jun 22, 2022	Held by the GJN 2021 TRUST	F1
transaction	OPK	Common Stock	Purchase	$33.1K	+13.2K	+0.07%	$2.50	19.9M	Jun 22, 2022	Held by the GJN 2021 TRUST	F1
transaction	OPK	Common Stock	Purchase	$77.4K	+31K	+0.16%	$2.50	19.8M	Jun 22, 2022	Held by the EGN 2021 TRUST	F2
transaction	OPK	Common Stock	Purchase	$38K	+15.2K	+0.08%	$2.50	19.8M	Jun 22, 2022	Held by the EGN 2021 TRUST	F2
transaction	OPK	Common Stock	Purchase	$84.4K	+33.8K	+0.17%	$2.50	19.9M	Jun 22, 2022	Held by the EGN 2021 TRUST	F2
transaction	OPK	Common Stock	Purchase	$198K	+80K		$2.47	80K	Jun 22, 2022	Held by Nabel Family Investments LLC	F3
holding	OPK	Common Stock						75.5K	Jun 22, 2022	Direct

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Shares held by the GJN 2021 TRUST for the benefit of the Reporting Person's spouse and descendants, and for which the Reporting Person's spouse serves as co-trustee together with an independent trustee. The Reporting Person's spouse and the independent trustee serve as investment advisors of the trust. The Reporting Person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.
F2	Shares held by the EGN 2021 TRUST for the benefit of the Reporting Person and his descendants, and for which an independent trustee has been appointed. The Reporting Person and the independent trustee serve as investment advisors of the trust. The Reporting Person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.
F3	Shares held by the Nabel Family Investments LLC, of which the Reporting Person is the manager with sole investment power and has an approximately 48% interest through the parent trust, the 2009 Nabel Family Children's Trust of which the Reporting Person has sole control, and sole investment power. The Reporting Per disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be dee admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.