Luisa M. Stamm - Mar 29, 2022 Form 4 Insider Report for ASSEMBLY BIOSCIENCES, INC. (ASMB)

Role: Chief Medical Officer
Signature: /s/ John O. Gunderson, as Attorney-in-Fact
Stock symbol: ASMB
Transactions as of: Mar 29, 2022
Transactions value $: -$2,250
Form type: 4
Date filed: 3/31/2022, 04:48 PM

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ASMB	Common Stock	Award	$0	+22.5K	+119.34%	$0.00	41.4K	Mar 29, 2022	Direct	F1
transaction	ASMB	Common Stock	Sale	-$2.25K	-1.04K	-2.51%	$2.17	40.3K	Mar 30, 2022	Direct	F2, F3

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ASMB	Stock Option (right to buy)	Award	$0	+90K		$0.00	90K	Mar 29, 2022	Common Stock	90K	$2.30	Direct	F4
transaction	ASMB	Performance-based Restricted Stock Units	Award	$0	+22.5K		$0.00	22.5K	Mar 29, 2022	Common Stock	22.5K		Direct	F5

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Grant of restricted stock units. The restricted stock units vest in four equal installments, assuming continuous service on each vesting date, as follows: March 29, 2023; March 29, 2024; March 29, 2025; and March 29, 2026.
F2	The sale reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person and represents shares sold to cover tax withholding obligations in connection with the vesting of restricted stock units.
F3	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $2.10 to $2.25, inclusive. The reporting person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within.
F4	Grant of stock options. The stock options vest over four years, assuming continuous service on each vesting date, as follows: 25% vest on the first anniversary of the date of grant, March 29, 2023; and the remaining 75% vest in 36 approximately equal monthly installments, with the options becoming fully vested on March 29, 2026.
F5	Each performance-based restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock. The shares are earned if either of two trading price metrics are met (each a "Stock Metric") either on or before the second or on or before the fourth anniversary of the grant date, as applicable. If a Stock Metric is met on or before the first anniversary of the grant date, then 50% of the RSUs vest on the first anniversary of the grant date and the remainder will vest on the second anniversary of the grant date. If a Stock Metric is achieved after the first anniversary of the grant date and on or before the fourth anniversary of the grant date, then 50% of the RSUs vest on the date that the Stock Metric is achieved and the remaining 50% of the RSUs vest on the first anniversary of the initial vesting date. Special vesting provisions apply in the case of a change in control transaction.