Michael J. Detke - Aug 10, 2021 Form 4 Insider Report for Cortexyme, Inc. (QNCX)

Role: Chief Medical Officer
Signature: /s/ Caryn Gordon McDowell, Attorney-in-Fact for Michael J. Detke, M.D.
Stock symbol: QNCX
Transactions as of: Aug 10, 2021
Transactions value $: -$977,700
Form type: 4
Date filed: 8/12/2021, 05:37 PM
Previous filing: Jul 7, 2021
Next filing: Jan 5, 2022

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	QNCX	Common Stock	Options Exercise	$22.3K	+10K		$2.23	10K	Aug 10, 2021	Direct
transaction	QNCX	Common Stock	Sale	-$1M	-10K	-100%	$100.00^*	0	Aug 10, 2021	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	QNCX	Stock Option (right to buy)	Options Exercise	$0	-10K	-9.77%	$0.00	92.4K	Aug 10, 2021	Common Stock	10K	$2.23	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 19, 2021.
F2	The option will vest as to 25% of the shares on November 15, 2019, with the remaining 75% of shares vesting in equal monthly installments beginning on December 15, 2019 and ending on November 15, 2022.