Kimberly Manhard - Jul 13, 2021 Form 4 Insider Report for HERON THERAPEUTICS, INC. /DE/ (HRTX)

Role: EVP, Drug Development, Director
Signature: /s/ Lisa Peraza Attorney-in-fact for Kimberly Manhard
Stock symbol: HRTX
Transactions as of: Jul 13, 2021
Transactions value $: -$5,837
Form type: 4
Date filed: 7/15/2021, 04:47 PM
Previous filing: Jun 8, 2021
Next filing: Oct 15, 2021

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	HRTX	Common Stock	Options Exercise		+1.25K	+76.5%		2.88K	Jul 13, 2021	Direct	F1
transaction	HRTX	Common Stock	Tax liability	-$5.84K	-433	-15.01%	$13.48^*	2.45K	Jul 13, 2021	Direct	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	HRTX	Restricted Stock Units	Options Exercise	$0	-1.25K	-7.14%	$0.00	16.3K	Jul 13, 2021	Common Stock	1.25K		Direct	F1, F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Restricted stock units convert into common stock on a one-for-one basis.
F2	Represents the withholding by the Company of certain of the vested shares of restricted stock to satisfy the minimum statutory tax obligations applicable to such transactions.
F3	The restricted stock units vest in 16 equal quarterly installments beginning three months after the date of grant (10/13/2020).