| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| ROSSI DINO A | Director | C/O KRYSTAL BIOTECH, INC., 2100 WHARTON STREET, SUITE 701, PITTSBURGH | /s/ Krish Krishnan, as attorney-in-fact for Dino A. Rossi | 23 Feb 2026 | 0001209059 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | KRYS | Common Stock | Options Exercise | $166,570 | +18,950 | +24% | $8.79 | 97,641 | 19 Feb 2026 | Direct | |
| transaction | KRYS | Common Stock | Sale | $2,114,103 | -8,116 | -8.3% | $260.49 | 89,525 | 19 Feb 2026 | Direct | |
| transaction | KRYS | Common Stock | Sale | $2,839,591 | -10,834 | -12% | $262.10 | 78,691 | 19 Feb 2026 | Direct | F1 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | KRYS | Stock Option (Right to Buy) | Options Exercise | $0 | -18,950 | -100% | $0.000000 | 0 | 19 Feb 2026 | Common Stock | 18,950 | $8.79 | Direct | F2 |
| Id | Content |
|---|---|
| F1 | Multiple lots for the same price for this transaction have been combined. |
| F2 | The options vested ratably over a four-year period beginning on June 1, 2018. |