Ian Michael Estepan - 25 Feb 2026 Form 4 Insider Report for Sarepta Therapeutics, Inc. (SRPT)

Role: Chief Operating Officer
Signature: /s/ Cristin L. Rothfuss, as Attorney-in-Fact for Ian Michael Estepan
Issuer symbol: SRPT
Transactions as of: 25 Feb 2026
Net transactions value: $0
Form type: 4
Filing time: 27 Feb 2026, 20:05:03 UTC
Previous filing: 18 Dec 2025
Next filing: 02 Mar 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Estepan Ian Michael	Chief Operating Officer	215 FIRST STREET, SUITE 415, CAMBRIDGE	/s/ Cristin L. Rothfuss, as Attorney-in-Fact for Ian Michael Estepan	27 Feb 2026	0001836254

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	SRPT	Performance Stock Units	Award		+1,875	+30%		8,125	25 Feb 2026	Common Stock	1,875		Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents the number of shares earned under a PSU award granted to the Reporting Person on March 1, 2024. The number of shares earned is based on the Compensation Committee's determination of the Company's achievement of the prescribed milestones under the terms of the PSU award. The earned PSUs will vest on March 1, 2026, subject to the Reporting Person continuing to provide service to the Company through such vesting date.

Content

Represents the number of shares earned under a PSU award granted to the Reporting Person on March 1, 2024. The number of shares earned is based on the Compensation Committee's determination of the Company's achievement of the prescribed milestones under the terms of the PSU award. The earned PSUs will vest on March 1, 2026, subject to the Reporting Person continuing to provide service to the Company through such vesting date.