Lee Kalowski - 25 Feb 2026 Form 4 Insider Report for Q32 Bio Inc. (QTTB)

Role: CFO and President
Signature: /s/ Eric Bell, Attorney-in-Fact
Issuer symbol: QTTB
Transactions as of: 25 Feb 2026
Net transactions value: -$18,035
Form type: 4
Filing time: 27 Feb 2026, 19:00:09 UTC
Previous filing: 04 Dec 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Kalowski Lee	CFO and President	Q32 BIO INC., 830 WINTER STREET, WALTHAM	/s/ Eric Bell, Attorney-in-Fact	27 Feb 2026	0001618273

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	QTTB	Common Stock	Sale	$18,035	-3,995	-10%	$4.51	35,943	25 Feb 2026	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.
F2	The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.35 to $4.69. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, on request, full information regarding the number of shares sold at each separate price within the range set forth above.

Content

Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.35 to $4.69. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, on request, full information regarding the number of shares sold at each separate price within the range set forth above.