Laurie Anne Lee - 26 Feb 2026 Form 3 Insider Report for Generate Biomedicines, Inc. (GENB)

Role: Chief Medical Officer
Signature: /s/ Michael Wolf, Attorney-in-Fact
Issuer symbol: GENB
Transactions as of: 26 Feb 2026
Net transactions value: $0
Form type: 3
Filing time: 26 Feb 2026, 20:46:23 UTC
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Lee Laurie Anne	Chief Medical Officer	GENERATE BIOMEDICINES, INC., 101 SOUTH STREET, SUITE 900, SOMERVILLE	/s/ Michael Wolf, Attorney-in-Fact	26 Feb 2026	0002112716

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
holding	GENB	Stock Option (Right to Buy)							26 Feb 2026	Common Stock	197,498	$9.15	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	25% of the shares underlying this option will vest on September 15, 2026 with the remainder vesting in twelve equal quarterly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

Remarks:

Exhibit 24 - Power of Attorney No securities are beneficially owned.