Craig A. Collard - 31 Jan 2026 Form 4 Insider Report for HERON THERAPEUTICS, INC. /DE/ (HRTX)

Role: Chief Executive Officer, Director
Signature: /s/Kathryn Lester Attorney-in-fact for Craig Collard
Issuer symbol: HRTX
Transactions as of: 31 Jan 2026
Net transactions value: $0
Form type: 4
Filing time: 03 Feb 2026, 08:30:06 UTC
Previous filing: 03 Feb 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Collard Craig A	Chief Executive Officer, Director	100 REGENCY FOREST DRIVE, SUITE 300, CARY	/s/Kathryn Lester Attorney-in-fact for Craig Collard	03 Feb 2026	0001363558

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	HRTX	Common Stock	Options Exercise		+34,789	+6.5%		571,710	31 Jan 2026	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	HRTX	Restricted Stock Units	Options Exercise	$0	-34,789	-7.7%	$0.000000	417,464	31 Jan 2026	Common Stock	34,789	$0.000000	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Each restricted stock unit represents a contingent right to receive one share of common stock.
F2	The restricted stock units vest in 16 equal installments beginning one quarter after the date of grant (January 31, 2025).