| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Lewicki John A. | Chief Scientific Officer | C/O MEREO BIOPHARMA GROUP PLC, 4TH FLOOR, ONE CAVENDISH PLACE, LONDON, UNITED KINGDOM | /s/ Christine Fox, by power of attorney | 02 Feb 2026 | 0001553352 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | MREO | Share Options (Right to buy) | Award | $0 | +139,913 | $0.000000 | 139,913 | 01 Feb 2026 | American Depositary Shares | 139,913 | $0.4400 | Direct | F1, F2 | |
| transaction | MREO | Share Options (Right to buy) | Award | $0 | +46,637 | $0.000000 | 46,637 | 01 Feb 2026 | American Depository Shares | 46,637 | $1.00 | Direct | F1, F2 | |
| transaction | MREO | Share Options (Right to buy) | Award | $0 | +145,000 | $0.000000 | 145,000 | 01 Feb 2026 | American Depository Shares | 145,000 | $0.4400 | Direct | F2, F3 |
| Id | Content |
|---|---|
| F1 | 25% of the shares underlying this share option will vest and become exercisable on February 1, 2027, with the remainder vesting in equal monthly installments for the three years thereafter. |
| F2 | Each American Depositary Share ("ADS") represents five ordinary shares, nominal value GBP 0.003 per ordinary share, of the Issuer. |
| F3 | Vests in substantially equal monthly installments over a one year period from the February 1, 2026 grant date. |