| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| CONTE LISA A | Chief Exec. Officer & President, Director | C/O JAGUAR HEALTH, INC., 200 PINE ST., STE 400, SAN FRANCISCO | /s/ Lisa A. Conte | 21 Jan 2026 | 0001008377 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | JAGX | Common Stock | Award | $0 | +28,592 | +4293% | $0.000000 | 29,258 | 11 Dec 2025 | Direct | F1, F2, F3 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | JAGX | Stock Option (right to buy) | Award | $0 | +28,592 | $0.000000 | 28,592 | 11 Dec 2025 | Common Stock | 28,592 | $1.44 | Direct | F1, F2, F4 |
| Id | Content |
|---|---|
| F1 | Granted pursuant to the issuer's 2014 Stock Incentive Plan. |
| F2 | The restricted stock unit and option grants were approved by the issuer's board of directors on December 11, 2025. |
| F3 | Each restricted stock unit represents a contingent right to receive one share of the issuer's voting common stock. The restricted stock units vest on December 11, 2026. Vested shares will be delivered to the reporting person on the vesting date provided in the grant notice. |
| F4 | The options will vest ratably on a monthly basis over 12 months from the grant date, so long as the executive remains employed by the issuer. |
Chief Exec. Officer & President